MFR said a man who was walking along the sidewalk near North East 39th Street and Biscayne Boulevard heard the kitten cries and called 911.
After 3 p.m. Wednesday, MFR's Technical Rescue Team arrived to find the kitten 10 feet below the street in the middle of the storm drain.
Using specialized equipment for confined space rescue, MFR said the firefighters were able to free the kitten and bring it to waiting paramedics.
Unable to locate the mother cat, MFR said the firefighters felt sympathy for the kitten and took it back to the fire station for a warm bath and food.
The firefighters said they will now try to find a home for the kitten.