Celebrities such as "American Idol" host Ryan Seacrest and "Brady Bunch" mom Florence Henderson will appear Sunday evening on the Muscular Dystrophy Association's nationally broadcast 48th annual telethon.
The "MDA Show of Strength" will appear on ABC, unlike in previous years when the telethon aired on various networks' affiliates.
Featured entertainers will include the Backstreet Boys, singer Paula Abdul, country star Lee Ann Womack and "The Voice" star Chris Mann.
The show is set to air from 9 p.m. to 11 p.m. in the Eastern and Pacific time zones and from 8 p.m. to 10 p.m. in the Central and Mountain regions.
This year's telethon is the third since comedian Jerry Lewis's 45-year role as host ended.
Kelli Park, a spokeswoman for the Tucson, Ariz.-based MDA, says the 2012 telethon raised $58.7 million.