Carlos Lee hit a grand slam and the Florida Marlins beat the Cubs 9-5 on Tuesday night, giving Ozzie Guillen a win in his first game back managing in Chicago.
Lee's slam against Travis Wood highlighted a five-run fifth and tied him with Jimmie Foxx and Ted Williams for seventh on baseball's career list with 17.
Omar Infante also homered and had three hits, giving him 17 in 36 at-bats at Wrigley Field. Hanley Ramirez also went deep in the game to back a strong start by Anibal Sanchez (5-6).
That had to please Guillen, who managed the White Sox for eight years before a messy split at the end of last season. He led the South Siders to a 678-617 record that included a championship in 2005, their first since 1917, but his tenure ended after his relationship with general manager Ken Williams disintegrated.