SAN DIEGO -

Jedd Gyorko hit two home runs off Jose Fernandez, leading Tyson Ross and the San Diego Padres to a 10-1 victory over the Miami Marlins on Friday night.

Gyorko, who came into the game hitting just .146, connected for a two-run shot in the second and a grand slam in the sixth. The six RBIs set a career high.

The Padres, who came in averaging a major league-low 2.6 runs per game, snapped a three-game losing streak. It was their highest-scoring game since a 12-2 victory over Arizona on Sept. 25.

San Diego sent 11 men to the plate during a six-run sixth inning that broke it open. The Padres' previous high for runs in a single game this season was six.