Sydney Towle, a social media content creator who projected enduring optimism as she chronicled her life with a rare form of cancer, has died, according to her family. She was 26.

Towle was diagnosed with cholangiocarcinoma, an aggressive form of cancer in the bile ducts, in August 2023. Her mother, Elizabeth Morrow, and brother, Austin Towle, posted a video to her TikTok account confirming she died Wednesday.

“Syd went peacefully last night after an almost three-year long battle with cholangiocarcinoma,” her brother said. “She fought really hard, and we’re so proud of her, and we thank all of you for your support over the years.” Towle's mother said they appreciated the messages of support and that “she will not be forgotten.”

Her family described her as “an endless ray of sunshine” and a friend to many. Sydney Elizabeth Towle was born in Newburyport, Massachusetts, on Nov. 15, 1999, and grew up in Hobe Sound, Florida, according to the New York Times. The newspaper reported that she died at the National Institutes of Health in Bethesda, Maryland.

At the time of her diagnosis, Towle already had a presence on social media where she shared videos from her everyday life. She often posted from the beach and loved the outdoors. She was an avid surfer and runner.

Once she received the diagnosis at age 23, she began posting her unvarnished reality of the disease and treatment while holding fast to her hobbies, style and positive attitude. She had over 1 million followers on TikTok alone.

In a video posted days after she was diagnosed, Towle said, “I’m in good spirits, I’m smiling. If anything, it just makes me appreciate life more.” That essentially became the ethos that guided her online presence, where she shared videos of herself running, going out with friends and traveling alongside videos from a hospital bed or at chemotherapy appointments.

In a column this year advocating for increased funding for research of the rare disease, Towle’s mother wrote that she had seen her daughter become “a beacon of hope for so many” through her candid online presence. “Thousands of people send her messages, stop her on the street and leave comments on her videos, describing how her vulnerability has helped them through their own struggles,” Morrow wrote in February.

Towle graduated from Dartmouth College in 2022, where she studied government and environmental studies. She worked as a social media manager at Epic Games.

She had posted on her LinkedIn account about plans to run the 2026 New York City Marathon in November to raise money for the Cholangiocarcinoma Foundation. She had raised more than $10,000 for the nonprofit that advocates for research and provides patients and caregivers with resources.

“I know it might seem crazy to try to run a marathon with everything going on,” she wrote on the platform months ago. But she noted the importance of hope in her experience with the disease. “Hope keeps us alive, it keeps us going, it makes the impossible seem possible.”

Towle is survived by her mother and brother. Her father, Philip Towle, died in 2016.

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